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THERAPEUTIC PROTOCOLS

The Neurobiological Modulation with REAC® Technology (Radio Electric Asymmetric Conveyer) is administered by means of the medical device of the series B.E.N.E. with specific therapeutic protocols developed to intervene in specific specialist medical fields.

Protocols-Therapeutics-REAC

NPPO

What it is:

TheNeuro-Physical Optimization (NPPO) It is a special protocol of Neuro Modulation which is implemented with the REAC technology®.
It is completely painless, lasts a few seconds, is free of side effects and the results are progressive over time.

For the patient consists in the positioning for a few moments of a probe tip of the equipment? B.E.N.E. (Bio Enhancer? Neuro Enhancer)  on specific areas of the earpiece, according to a precise procedure. 

NPPO is administered in therapeutic cycles, each consisting of 18 sessions. Normally there are always more therapeutic cycles that vary depending on the state of health or disease of the person being treated.

What it is for:

It serves to determine a progressive Optimization of neurological, psychic and physical functions both in healthy subjects and with diseases of various kinds.

In summary, we can say that the Effects of therapy Neuro-Physical Optimization are:

  1. A progressive improvement in the state of general health and in particular psycho-emotional behavior;
  2. Reduction and / or disappearance of some symptoms and a progressive improvement of pathological frameworks with consequent reduction of the abuse of some drugs.

Method of administration:

It is carried out by sequentially applying the point probe (handpiece), on 7 precise points of the ear.

Duration of the sitting:

Each application point requires 500 ms. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

Each therapeutic cycle consists of 18 sessions. The interval between sessions should never exceed 2 weeks. We recommend 1 to 3 clicks per year in relation to the patient's clinical picture.

NPPO-CB

What it is:

TheNeuro-Physical Optimization Cervical Brachial (NPPO-CB) It is a special protocol of Neuro Modulation which is implemented with the REAC technology®.
It is completely painless, lasts a few minutes, is free of side effects and the results are progressive over time.

For the patient it consists in wearing a special probe made of antibacterial conductive material A.C.P. (Asymmetric Conveyer Probe). Does the treatment last a few minutes and is it managed by the equipment? B.E.N.E. (Bio Enhancer? Neuro Enhancer) according to a precise procedure. 

What it is for:

It serves to determine a progressive Optimization of neurological, psychic and physical functions both in healthy subjects and with diseases of various kinds. Compared to the NPPO protocol, NPPO-CB focuses more on subcortical structures. As a result of this peculiarity NPPO and NPPO-CB are often administered in pairs to maximize the effects of optimization.

In summary, we can say that the Effects of therapy Neuro-Physical Optimization Cervical Brachial are:

  1. A progressive improvement in the state of general health and in particular psycho-emotional behavior;
  2. Reduction and / or disappearance of some symptoms and a progressive improvement of pathological frameworks with consequent reduction of the abuse of some drugs.

Method of administration:

The application is carried out after placing the appropriate ACP on the cervico-brachial area.

Duration of the sitting:

4 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

Each therapeutic cycle consists of 18 sessions. The interval between sessions should never exceed 2 weeks. We recommend 1 to 3 clicks per year in relation to the patient's clinical picture.

NPPO-BWO

What it is:

TheNeuro-Physical Optimization? Brain Rhythm Optimization (NPPO-BWO) It is a special protocol of Neuro Modulationwhich is implemented with the REAC technology®.

It is a large family of protocols. Neuro Modulation aimed at the functional reorganization of brain rhythms (Delta, Theta, Alpha, Beta and Gamma).

The administration of these treatments is completely painless and non-invasive. Each treatment lasts a few minutes, the results are progressive over time.

For the patient it consists in wearing a special surface probe made of antibacterial conductive material A.C.P. (Asymmetric Conveyer Probe). 

Does the treatment last a few minutes and is it managed by the equipment? B.E.N.E. (Bio Enhancer? Neuro Enhancer) according to a precise procedure.

What it is for:

Neuro-Physical Optimisation and Brain Rhythm Optimisation can help to:

  1. A progressive improvement in the state of general health and in particular psycho-emotional behavior;
  2. Reduction and / or disappearance of some symptoms and a progressive improvement of pathological frameworks with consequent reduction of the abuse of some drugs.

Method of administration:

The application is carried out after placing the appropriate ACP on the treatment area.

Duration of the sitting:

4 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

Each therapeutic cycle consists of 18 sessions. The interval between sessions should never exceed 2 weeks. We recommend 1 to 3 clicks per year in relation to the patient's clinical picture.

NPO

What it is:

TheNeuro Postural Optimization (NPO) is a sophisticated neuromodulation protocol that is implemented with the REAC technology®. It is completely painless, lasts a few moments, is free of side effects and the results tend to be stable over time.
Due to the stability of the effects, it is very rarely necessary to repeat the Neuro Postural Optimization treatment.
For the patient is the placement for a few milliseconds of a probe tip of the equipment? B.E.N.E. (Bio Enhancer? Neuro Enhancer) on a specific area of the auricle.

What it is for:

It is used to determine the beginning of the processes of optimization of neuromotor and neuropsychic functions.
Sometimes the only Neuro Postural Optimization can determine important phenomena of functional recovery and reduction of some symptoms.

Some examples of immediate effects of Neuro Postural Optimization:

  • improvement of postural attitude;
  • immediate reduction of some algic symptoms;
  • immediate recovery of better motor strategies in the healthy subject;
  • immediate recovery of better motor strategies in the pathological subject, for example in spasticities of various kinds.

Method of administration:

The application is carried out with the handpiece for point application on a precise point of the earpiece.

Duration of the sitting:

The application is unique and lasts only 250 ms.

Therapeutic cycle:

The cliché is composed of only one seat as the effect is stable over time.

NMO

What it is:

Neuromuscular Optimization (NMO) is the name that brings together a set of Therapeutic protocols of Neuro Modulation applicable only with the REAC technology®, with a view to optimising the Muscle Management, in particular the functional balance between agonist and antagonistic muscles, both in pathological and dysfunctional frameworks.
 
Neuromuscular Optimization is a New Paradigm in the context of Advanced Rehabilitation, opening up new concrete perspectives and rehabilitative therapeutic possibilities.
 
Normally there are always more therapeutic cycles that vary depending on the state of health or disease of the person being treated.
 
Neuromuscular Optimization Therapies cover the areas to be treated with a special surface probe called A.C.P (Asymmetric Conveyer Probe) connected to the REAC device? B.E.N.E. (Bio Enhancer Neuro Enhancer).
 

What it is for:

It is used to optimize the management of muscles and therefore of movements, allowing a gradual and progressive correction of neuro-psycho-motor alterations and the recovery of a correct and balanced muscular and postural management.

Method of administration:

It is performed using the ACP positioned so as to treat the contralateral antagonistic muscles.

Duration of the sitting:

8 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

Each therapeutic cycle consists of 12 sessions. The interval between sessions should never exceed 2 weeks. We recommend 1 to 3 clicks per year in relation to the patient's clinical picture.

NPPO

What it is:

TheNeuro-Physical Optimization (NPPO) It is a special protocol of Neuro Modulation which is implemented with the REAC technology®.
It is completely painless, lasts a few seconds, is free of side effects and the results are progressive over time.

For the patient consists in the positioning for a few moments of a probe tip of the equipment? B.E.N.E. (Bio Enhancer? Neuro Enhancer)  on specific areas of the earpiece, according to a precise procedure. 

NPPO is administered in therapeutic cycles, each consisting of 18 sessions. Normally there are always more therapeutic cycles that vary depending on the state of health or disease of the person being treated.

What it is for:

It serves to determine a progressive Optimization of neurological, psychic and physical functions both in healthy subjects and with diseases of various kinds.

In summary, we can say that the Effects of therapy Neuro-Physical Optimization are:

  1. A progressive improvement in the state of general health and in particular psycho-emotional behavior;
  2. Reduction and / or disappearance of some symptoms and a progressive improvement of pathological frameworks with consequent reduction of the abuse of some drugs.

Method of administration:

It is carried out by sequentially applying the point probe (handpiece), on 7 precise points of the ear.

Duration of the sitting:

Each application point requires 500 ms. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

Each therapeutic cycle consists of 18 sessions. The interval between sessions should never exceed 2 weeks. We recommend 1 to 3 clicks per year in relation to the patient's clinical picture.

NPPO-CB

What it is:

TheNeuro-Physical Optimization Cervical Brachial (NPPO-CB) It is a special protocol of Neuro Modulation which is implemented with the REAC technology®.
It is completely painless, lasts a few minutes, is free of side effects and the results are progressive over time.

For the patient it consists in wearing a special probe made of antibacterial conductive material A.C.P. (Asymmetric Conveyer Probe). Does the treatment last a few minutes and is it managed by the equipment? B.E.N.E. (Bio Enhancer? Neuro Enhancer) according to a precise procedure. 

What it is for:

It serves to determine a progressive Optimization of neurological, psychic and physical functions both in healthy subjects and with diseases of various kinds. Compared to the NNPO protocol, NNPO-CB focuses more on subcortical structures. As a result of this peculiarity NPPO and NPPO-CB are often administered in pairs to maximize the effects of optimization.

In summary, we can say that the Effects of therapy Neuro-Physical Optimization Cervical Brachial are:

  1. A progressive improvement in the state of general health and in particular psycho-emotional behavior;
  2. Reduction and / or disappearance of some symptoms and a progressive improvement of pathological frameworks with consequent reduction of the abuse of some drugs.

Method of administration:

The application is carried out after placing the appropriate ACP on the cervico-brachial area.

Duration of the sitting:

4 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

Each therapeutic cycle consists of 18 sessions. The interval between sessions should never exceed 2 weeks. We recommend 1 to 3 clicks per year in relation to the patient's clinical picture.

ANM

What it is:

Neuro-anthalgic modulation is the name that brings together a set of treatments, possible with specific protocols of the REAC technology®, aimed at relieving various painful pictures, when symptom pain itself becomes a disease to be cured.

Normally there are always more therapeutic cycles that vary depending on the state of health or disease of the person being treated.

The therapies of Neuro Antalgic Modulation are carried out by covering the area to be treated with a special surface electrode A.C.P. (Asymmetric Conveyer Probe) patent claim, related to the equipment? B.E.N.E. (Bio Enhancer Neuro Enhancer) necessary for the administration of Neuro Modulation protocols with REAC® Technology.

What it is for:

It serves to treat various painful pictures, which do not benefit from other treatments.

Method of administration:

This treatment is carried out using the ACP positioned on the algal areas to be treated.

Duration of the sitting:

15 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

Each therapeutic cycle consists of 10 - 20 sessions. The interval between sessions should never exceed 2 weeks. We recommend 1 to 3 clicks per year in relation to the patient's clinical picture.

TO-B

What it is:

TheBasic Tissue Optimization It is a sophisticated protocol of Bio Modulation which is implemented with the REAC technology?. It's totally painless and free of side effects.
 
For the patient it consists in the placement for a few minutes of a special surface electrode A.C.P. (Asymmetric Conveyer Probe) connected to the equipment B.E.N.E. (Bio Enhancer? Neuro Enhancer)  on a specific area of the body to be treated.

 

What it is for:

It is the therapy commonly used in the general clinical setting, to treat the results of traumatism and inflammatory, acute and chronic situations.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

8 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

18 sessions

TO-RPR

What it is:

TheRepair Tissue Optimization (TO-RPR) is a specific advanced treatment to promote the repair of both superficial and deep tissues such as bones, muscles, internal organs by restoring normal endogenous bioelectric activity.

For the patient it consists in the positioning for a few minutes of a special probe A.C.P. (Asymmetric Conveyer Probe) connected to the equipment B.E.N.E. (Bio Enhancer? Neuro Enhancer)  on a specific area of the body to be treated.

What it is for:

Reparative Tissue Optimization is indicated to promote the repair of both superficial and deep tissues.
It also finds an important indication, as a basic protocol, in the medicine of anti-aging.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

15 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

18 sessions

TO-CO

What it is:

TheCirculatory Optimization (CO) is an advanced Bio Modulation protocol applicable with the REAC technology? through a special A.C.P. (Asymmetric Conveyer Probe).
The therapy is administered in cycles of sessions, which vary according to the patient's picture.

 

What it is for:

The Circulatory Optimization protocol is specific to promote the improvement of circulation, both in superficial and deep tissues, in all those areas where this type of treatment can be useful.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

15 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

18 sessions

TO-MO

What it is:

TheMetabolic Optimization (MO) is an advanced Bio Modulation protocol applicable with the REAC technology? through a special A.C.P. (Asymmetric Conveyer Probe).
The therapy is administered in cycles of sessions, which vary according to the patient's picture.

 

What it is for:

The Protocol MO promotes the improvement of both superficial and deep tissues by normalizing cellular metabolism.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

15 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

18 sessions

TO-ACT

What is it:

The treatment of Anti-Cellulite Tissue Optimization (TO-ACT) is a useful treatment for superficial and medium tissues with a prevalence of the fibrotic component.

For the patient it consists in the positioning for a few minutes of a special probe A.C.P. (Asymmetric Conveyer Probe) connected to the equipment B.E.N.E. (Bio Enhancer? Neuro Enhancer)  on a specific area of the body to be treated.

 

What it is for:

TO-ACT is a treatment that is applied selectively when a tissue has cellulite reactions and signs of fibrosis resulting from previous chronic inflammatory processes.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

15 minutes per session. It is possible to carry out up to 4 sessions per day with an interval of at least one hour between them.

Therapeutic cycle:

18 sessions

TO-RGN

What is it:

The treatment of Regenerative Tissue Optimization (TO-RGN) is a family of scientifically advanced therapeutic protocols. and validated under the Regenerative medicine.

What it is for:

The protocols of the Regenerative Tissue Optimisation family serve to stimulate the regeneration of superficial, medium and deep tissues with a prevalence of the chronic lesion component.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

The duration of the sessions are determined on the basis of the treatment to be carried out and the specific protocol chosen.

Therapeutic cycle:

The number of sessions is evaluated after the specialist visit.

TO-RGN N

What is it:

The treatment of Regenerative Tissue Optimization (TO-RGN) is currently the most innovative, advanced and scientifically validated treatment in Regenerative Medicine.

What it is for:

The protocols of the Regenerative Tissue Optimisation family serve to stimulate the regeneration of superficial, medium and deep tissues with a prevalence of the chronic lesion component.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

The duration of the sessions are determined on the basis of the treatment to be carried out and the specific protocol chosen.

Therapeutic cycle:

The number of sessions is evaluated after the specialist visit.

TO-RGN AG

What is it:

The treatment of Regenerative Tissue Optimization (TO-RGN) is currently the most innovative, advanced and scientifically validated treatment in Regenerative Medicine.

What it is for:

The protocols of the Regenerative Tissue Optimisation family serve to stimulate the regeneration of superficial, medium and deep tissues with a prevalence of the chronic lesion component.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

The duration of the sessions are determined on the basis of the treatment to be carried out and the specific protocol chosen.

Therapeutic cycle:

The number of sessions is evaluated after the specialist visit.

TO-RGN HF

What is it:

The treatment of Regenerative Tissue Optimization (TO-RGN) is currently the most innovative, advanced and scientifically validated treatment in Regenerative Medicine.

What it is for:

The protocols of the Regenerative Tissue Optimisation family serve to stimulate the regeneration of superficial, medium and deep tissues with a prevalence of the chronic lesion component.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

The duration of the sessions are determined on the basis of the treatment to be carried out and the specific protocol chosen.

Therapeutic cycle:

The number of sessions is evaluated after the specialist visit.

TO-RGN AR

What is it:

The treatment of Regenerative Tissue Optimization (TO-RGN) is currently the most innovative, advanced and scientifically validated treatment in Regenerative Medicine.

What it is for:

The protocols of the Regenerative Tissue Optimisation family serve to stimulate the regeneration of superficial, medium and deep tissues with a prevalence of the chronic lesion component.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

The duration of the sessions are determined on the basis of the treatment to be carried out and the specific protocol chosen.

Therapeutic cycle:

The number of sessions is evaluated after the specialist visit.

TO-RGN C

What is it:

The treatment of Regenerative Tissue Optimization (TO-RGN) is currently the most innovative, advanced and scientifically validated treatment in Regenerative Medicine.

What it is for:

The protocols of the Regenerative Tissue Optimisation family serve to stimulate the regeneration of superficial, medium and deep tissues with a prevalence of the chronic lesion component.

Method of administration:

The ACP probe shall be positioned on the area to be treated.

Duration of the sitting:

The duration of the sessions are determined on the basis of the treatment to be carried out and the specific protocol chosen.

Therapeutic cycle:

The number of sessions is evaluated after the specialist visit.

Dr. Vania Fontani

Doctor Surgeon
Neurophysiopathologist
Physical Medicine and Rehabilitation
Master II Liv. in Neuro Psycho Pathophysiology and Optimization Neuro Physical Psycho

Register of Professional Association of Physicians of Florence and Province No. 9096

Co-founder and Health Director of the Rinaldi Fontani Institute

Co-founder and Scientific Director of IRF Shanghai Medical Science Co., Ltd – Shanghai, China

President of the Italian Society of Neuro-Psycho-Physical Optimization (SONC)

Vice President of the International Society of Neuroscience for Neuro Psycho Physical Optimization (ISNPO)

 

Professional path:

Since 1989 he has been a lecturer in second-level university master’s degrees and university master’s courses on adaptive neurophysiopathology and neuro-psycho-physical optimisation at the faculties of Medicine and Surgery G. D’Annunzio – Chieti, Tor Vergata – Rome and Florence.
Speaker at national and international congresses.
In his research activity he defined four international patents concerning the technology of conveyed radio fields and the modulation of cellular reprogramming through these. It also defined a national patent for a measuring instrument for anatomical-functional misalignments.

 

Publications in international peer reviewed scientific journals indexed on PubMed:

Long-Lasting Efficacy of Radio Electric Asymmetric Conveyer Neuromodulation Treatment on Functional Dysmetria, an Adaptive Motor Behavior. Fontani V, Rinaldi A, Rinaldi C, et al. Cureus. 2022 Jun 8; 14(6): e25768. doi:10.7759/cureus.25768

Radio Electric Asymmetric Conveyer Tissue Reparative Treatment on Post-surgical Breast Skin Necrosis. A Report of Four Cases. Fontani V, Coelho Pereira JA, Rinaldi S. Cureus. 2022 Jun 5;14(6):e25666. doi: 10.7759/cureus.25666. eCollection 2022 Jun.

Radio Electric Asymmetric Conveyer Reparative Effects on Muscle Injuries: A Report of Two Cases. Chestnut A, Fontani V, Rinaldi S. Cureus. 2022 May 11;14(5):e24904. doi: 10.7759/cureus.24904. eCollection 2022 May.



REAC-induced endogenous bioelectric currents in the treatment of venous ulcers: a three-arm randomized controlled prospective study. Elio C, Fontani V, Rinaldi S, Gasbarro V. Acta Dermatovenerol Alp Pannonica Adriat. 2020 Sep;29(3):109-113. PMID: 32975296.

REAC neurobiological treatments in acute post-traumatic knee medial collateral ligament lesion. Barcessat ARP, Bittencourt MN, Pereira JAC, Castagna A, Fontani V, Rinaldi S. Heliyon. 2020 Jul 24;6(7):e04539. doi: 10.1016/j.heliyon.2020.e04539. PMID: 32743108; PMCID: PMC7385461.

Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress. Rinaldi A, Rinaldi C, Coelho Pereira JA, Lotti Margotti M, Bittencourt MN, Barcessat ARP, Fontani V, Rinaldi S. Neuropsychiatric Disease and Treatment 2019:15 469?480.

Physical stimulation by REAC and BMP4/WNT-1 inhibitor synergistically enhance cardiogenic commitment in iPSCs. Basoli V, Santaniello S, Rinaldi S, Fontani V, Pigliaru G, Wieser M, Strajeriu A, Castagna A, Redl H, Ventura C, Grillari R, Maioli M.
PLoS One. 2019 Jan 23;14(1):e0211188. doi: 10.1371/journal.pone.0211188. eCollection 2019.

Radio Electric Asymmetric Conveyer (REAC) technology to obviate loss of T cell responsiveness under simulated microgravity. Rinaldi S, Meloni MA, Galleri G, Maioli M, Pigliaru G, Cugia G, Santaniello S, Castagna A, Fontani V. PLoS One. 2018 Jul 6;13(7):e0200128. doi: 10.1371/journal.pone.0200128. eCollection 2018.

REAC neuromodulation treatments in subjects with severe socio-economic and cultural hardship in the Brazilian state of Pará: A family observational pilot study. Coelho Pereira JA, Rinaldi A, Fontani V, Rinaldi S. Neuropsychiatr Dis Treat. 2018 Apr 16;14:1047-1054.
doi: 10.2147/NDT.S161646. eCollection 2018.

Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a Mouse Model of Neurodegeneration.
Panaro MA, Aloisi A, Nicolardi G, Lofrumento DD, De Nuccio F, La Pesa V, Cianciulli A, Rinaldi R, Calvello R, Fontani V, Rinaldi S. Neurosci Bull. 2017 Nov 10. doi: 10.1007/s12264-017-0188-0.

REAC technology as optimizer of stallion spermatozoa liquid storage. Berlinguer F, Pasciu V, Succu S, Cossu I, Caggiu S, Addis D, Castagna A, Fontani V, Rinaldi S, Passino ES. Reprod Biol Endocrinol. 2017 Feb 8;15(1):11. doi: 10.1186/s12958-017-0229-6.

REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer’s disease mouse model. Lorenzini L, Giuliani A, Sivilia S, Baldassarro VA, Fernandez M, Margotti ML, Giardino L, Fontani V, Rinaldi S, Calzà L. Sci Rep. 2016 Nov 18;6:37483. doi: 10.1038/srep37483.

REAC technology and hyaluron synthase 2, an interesting network to slow down stem cell senescence. Maioli M, Rinaldi S, Pigliaru G, Santaniello S, Basoli V, Castagna A, Fontani V, Ventura C. Sci Rep. 2016 Jun 24;6:28682.

Osteogenesis from Dental Pulp Derived Stem Cells: A Novel Conditioned Medium Including Melatonin within a Mixture of Hyaluronic, Butyric, and Retinoic Acids.Maioli M, Basoli V, Santaniello S, Cruciani S, Delitala AP, Pinna R, Milia E, Grillari-Voglauer R, Fontani V, Rinaldi S, Muggironi R, Pigliaru G, Ventura C. Stem Cells Int. 2016;2016:2056416. doi: 10.1155/2016/2056416. Epub 2016 Jan 10.

Electrophysiological effects of non-invasive Radio Electric Asymmetric Conveyor (REAC) on thalamocortical neural activities and perturbed experimental conditions. Zippo AG, Rinaldi S, Pellegata G, Caramenti GC, Valente M, Fontani V, Biella GE. Ski Rep. 2015 Dec 11;5:18200.

Neurological morphofunctional differentiation induced by REAC technology in PC12. A neuro protective model for Parkinson’s disease. Maioli M, Rinaldi S, Migheli R, Pigliaru G, Rocchitta G, Santaniello S, Basoli V, Castagna A, Fontani V, Ventura C, Serra PA. Ski Rep. 2015 May 15;5:10439. doi: 10.1038/srep10439.

Radio electric asymmetric conveyer: a novel neuromodulation technology in Alzheimer’s and other neurodegenerative diseases. Rinaldi S, Calzà L, Giardino L, Biella GE, Zippo AG, Fontani V. Front Psychiatry. 2015 Feb 17;6:22.

Stem cell senescence. Effects of REAC technology on telomerase-independent and telomerase-dependent pathways. Rinaldi S, Maioli M, Pigliaru G, Castagna A, Santaniello S, Basoli V, Fontani V, Ventura C. Sci Rep. 2014 Sep 16;4:6373.

Long-lasting changes in brain activation induced by a single REAC technology pulse in Wi-Fi bands. Randomized double-blind fMRI qualitative study. Rinaldi S, Mura M, Castagna A, Fontani V. Sci Rep. 2014 Jul 11;4:5668. doi: 10.1038/srep05668.

Motor Effects of Radio Electric Asymmetric Conveyer in Alzheimer’s Disease: Results from a Cross-Over Trial. Olazarán J, González B, Osa-Ruiz E, Felipe-Ruiz S, Boyano I, Fontani V, Castagna A, Mendoza C, Zea MA, Frades B, Rinaldi S, Martínez-Martín P. J Alzheimers Dis. 2014 May 30.

Radio electric asymmetric conveyed fields and human adipose-derived stem cells grown with a non-enzymatic method and device: A novel approach to multipotency. Maioli M, Rinaldi S, Santaniello S, Castagna A, Pigliaru G, Delitala A, Bianchi F, Tremolada C, Fontani V, Ventura C. Cell Transplant. 2013 Aug 30.

Effects of regenerative radioelectric asymmetric conveyer treatment on human normal and osteoarthritic chondrocytes exposed to IL-1?. A biochemical and morphological study.
Collodel G, Fioravanti A, Pascarelli NA, Lamboglia A, Fontani V, Maioli M, Santaniello S, Pigliaru G, Castagna A, Moretti E, Iacoponi F, Rinaldi S, Ventura C.Clin Interv Aging. 2013;8:309-16. doi: 10.2147/CIA.S42229. Epub 2013 Mar 19.

Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Maioli M, Rinaldi S, Santaniello S, Castagna A, Pigliaru G, Delitala A, Lotti Margotti M, Bagella L, Fontani V, Ventura C. Age (Dordr). 2013 May 9.

Physical reparative treatment in reptiles.
Rinaldi S, Iannaccone M, Magi GE, Costantini E, Castagna A, Sanna Passino E, Maioli M, Fontani V.
BMC Vet Res. 2013 Feb 26;9(1):39.

The effect of radio electric asymmetric conveyer treatment on sperm parameters of subfertile stallions: A pilot study. Collodel G, Rinaldi S, Moretti E, Fontani V, Castagna A, Iacoponi F, Terzuoli G, Cubeddu F, Careddu GM, Cossu I, Passino ES. Reprod Biol. 2012 Nov;12(3):277-84. Epub 2012 Oct 22.

Radio Electric Conveyed Fields Directly Reprogram Human Dermal-Skin Fibroblasts Towards Cardiac-, Neuronal-, and Skeletal Muscle-Like Lineages. Maioli M, Rinaldi S, Santaniello S, Castagna A, Pigliaru G, Gualini S, Cavallini C, Fontani V, Ventura C. Cell Transplant. 2012 Oct 2.

Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study. Rinaldi S, Maioli M, Santaniello S, Castagna A, Pigliaru G, Gualini S, Margotti ML, Carta A, Fontani V, Ventura C. Clin Interv Aging. 2012;7:191-4. Epub 2012 Jun 29.

Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetry. Mura M, Chestnut A, Fontani V, Rinaldi S. Neuropsychiatr Dis Treat. 2012;8:149-54. Epub 2012 Apr 4.

Neuropsychophysical optimization by REAC technology in the treatment of: Sense of stress and confusion. Psychometric evaluation in a randomized, single blind, sham-controlled naturalistic study. Fontani V, Aravagli L, Margotti ML, Castagna A, Mannu P, Rinaldi S. Patient Prefer Adherence. 2012;6:195-9. Epub 2012 Mar 19.

Noninvasive radioelectric asymmetric conveyor brain stimulation treatment improves balance in individuals over 65 suffering from neurological diseases: Pilot study. Fontani V, Rinaldi S, Castagna A, Margotti ML. Ther Clin Risk Manag. 2012;8:73-8. Epub 2012 Feb 17.

Social Anxiety Disorder: radio electric asymmetric conveyor brain stimulation versus sertraline. Fontani V, Mannu P, Castagna A, Rinaldi S. Patient Prefer Adherence. 2011;5:581-6. Epub 2011 Nov 22.

Noninvasive brain stimulation by radioelectric asymmetric conveyor in the treatment of agoraphobia: open-label, naturalistic study. Mannu P, Rinaldi S, Fontani V, Castagna A, Margotti ML. Patient Prefer Adherence. 2011;5:575-80. Epub 2011 Nov 18.

Brain activity modification produced by a single radioelectric asymmetric brain stimulation pulse: a new tool for neuropsychiatric treatments. Preliminary fMRI study. Rinaldi S, Fontani V, Chestnut A. Neuropsychiatr Dis Treat. 2011;7:649-54. Epub 2011 Oct 28.

Noninvasive radioelectric asymmetric brain stimulation in the treatment of stress-related pain and physical problems: Psychometric evaluation in a randomized, single-blind placebo-controlled, naturalistic study. Fontani V, Rinaldi S, Aravagli L, Mannu P, Castagna A, Margotti ML. Int J Gen Med. 2011;4:681-6. Epub 2011 Sep 22.

Radio Frequency Energy Loop Primes Cardiac, Neuronal, and Skeletal Muscle Differentiation in Mouse Embryonic Stem Cells: A New Tool for Improving Tissue Regeneration.
Maioli M, Rinaldi S, Santaniello S, Castagna A, Pigliaru G, Gualini S, Fontani V, Ventura C. Cell Transplant. 2011 Sep 22.

Radioelectric asymmetric stimulation of tissues as treatment for post-traumatic injury symptoms. Fontani V, Castagna A, Mannu P, Rinaldi S. Int J Gen Med. 2011;4:627-34. Epub 2011 Aug 26.

Radio electric tissue optimization in the treatment of surgical wounds. Chestnut A, Fontani V, Rinaldi S, Mannu P. Clin Cosmet Investig Dermatol. 2011;4:133-7. Epub 2011 Aug 25.

Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: A pilot study. Olivieri EB, Vecchiato C, Ignaccolo N, Mannu P, Castagna A, Aravagli L, Fontani V, Rinaldi S. Neuropsychiatr Dis Treat. 2011;7:449-55. Epub 2011 Aug 4.

Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor. Mannu P, Rinaldi S, Fontani V, Chestnut A .Neuropsychiatr Dis Treat. 2011;7:373-9. Epub 2011 Jun 15.

Radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in Alzheimer's disease. Mannu P, Rinaldi S, Fontani V, Castagna A.
Clin Interv Aging. 2011;6:207-11. Epub 2011 Jul 26.

Comparison of two treatments for coxarthrosis: local hyperthermia versus radio electric asymmetrical brain stimulation. Chestnut A, Rinaldi S, Fontani V, Mannu P, Margotti ML.
Clin Interv Aging. 2011;6:201-6. Epub 2011 Jul 25.

Radioelectric asymmetric brain stimulation and lingual apex repositioning in patients with atypical deglutition. Chestnut A, Rinaldi S, Fontani V, Mannu P. J Multidiscip Healthc. 2011;4:209-13. Epub 2011 Jun 21.

Stress-related psycho-physiological disorders: randomized single blind placebo controlled naturalistic study of psychometric evaluation using a radio electric asymmetric treatment.
Rinaldi S, Fontani V, Aravagli L, Mannu P, Castagna A, Margotti ML, Rosettani B. Health Qual Life Outcomes. 2011 Jul 19;9:54.

Psychological and symptomatic stress-related disorders with radio-electric treatment: Psychometric evaluation. Rinaldi S, Fontani, V., Aravagli, L., Lotti Margotti, M. Stress and Health. 2010;26(5):350-358.

A new approach on stress-related depression & anxiety: Neuro-Psycho-Physical-Optimization with Radio Electric Asymmetric-Conveyer. Rinaldi S, Fontani V, Moretti E, Rosettani B, Aravagli L, Saragò G, Collodel G. Indian J Med Res. 2010 Aug;132:189-94.

Does osteoarthritis of the knee also have a psychogenic component? Psycho-emotional treatment with a radio-electric device vs. intra-articular injection of sodium hyaluronate: an open-label, naturalistic study. Chestnut A, Rinaldi S, Fontani V, Aravagli L, Mannu P, Margotti ML. Acupunct Electrother Res. 2010;35(1-2):1-16.

Psychometric evaluation of a radio electric auricular treatment for stress related disorders: a double-blinded, placebo-controlled pilot study. Rinaldi S, Fontani V, Aravagli L, Mannu P. Health Qual Life Outcomes. 2010 Mar 20;8:31.

Radio electric treatment vs. Es-Citalopram in the treatment of panic disorders associated with major depression: an open-label, naturalistic study. Mannu P, Rinaldi S, Fontani V, Castagna A, Margotti ML. Acupunct Electrother Res. 2009;34(3-4):135-49.

Effect of emotional stress on sperm quality. Collodel G, Moretti E, Fontani V, Rinaldi S, Aravagli L, Saragò G, Capitani S, Anichini C. Indian J Med Res. 2008 Sep;128(3):254-61.

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